The synthesis of hydroxymethylenebisphosphonic- (dronic-) and acyl-ethoxycarbonyl-methylphosphonate derivatives

Recent results on the synthesis of substituted hydroxymethylenebisphosphonic acids (A and B), as well as acylated ethoxycarbonyl-methylphosphonate derivatives (C and D) are summarized. In the first part, solvent mixtures were applied in the preparation of known dronic acids, while in the second seri...

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Published inPhosphorus, sulfur, and silicon and the related elements Vol. 197; no. 5-6; pp. 520 - 522
Main Authors Keglevich, György, Szalai, Zsuzsanna, Gulyás, Kinga V., Zahár, Róbert, Grün, Alajos, Für, Csilla Sepsey
Format Journal Article
LanguageEnglish
Published Abingdon Taylor & Francis Ltd 22.06.2022
Subjects
Synthesis
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Summary:Recent results on the synthesis of substituted hydroxymethylenebisphosphonic acids (A and B), as well as acylated ethoxycarbonyl-methylphosphonate derivatives (C and D) are summarized. In the first part, solvent mixtures were applied in the preparation of known dronic acids, while in the second series of experiments, new acyl species were synthesized.
ISSN:1042-6507
1563-5325
DOI:10.1080/10426507.2021.2011873