Nanotherapeutics: Engineering Cell Membrane‐Based Nanotherapeutics to Target Inflammation (Adv. Sci. 15/2019)

In article number 1900605, Dan Shao, Kam W. Leong, and co‐workers summarize recent advances of rationally engineered cell membrane–based nanotherapeutics for inflammation therapy. These therapies utilize a functional nanoparticle core decorated with engineered cell‐membrane vesicles. Nanoparticle co...

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Bibliographic Details
Published inAdvanced science Vol. 6; no. 15
Main Authors Yan, Huize, Shao, Dan, Lao, Yeh‐Hsing, Li, Mingqiang, Hu, Hanze, Leong, Kam W.
Format Journal Article
LanguageEnglish
Published Hoboken John Wiley and Sons Inc 07.08.2019
Subjects
biomimetic nanomedicine
cell membrane engineering
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inflammation
inflammatory microenvironment
targeted drug delivery
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Summary:In article number 1900605, Dan Shao, Kam W. Leong, and co‐workers summarize recent advances of rationally engineered cell membrane–based nanotherapeutics for inflammation therapy. These therapies utilize a functional nanoparticle core decorated with engineered cell‐membrane vesicles. Nanoparticle cores that are organic (polymer), inorganic (silica and metal nanoparticle), or hybrid (such as metal–organic frameworks) in nature are all applicable. With judicious choice of cell membranes, these nanotherapeutics can achieve targeted delivery to the inflammatory environment for enhanced therapeutic efficacy.
ISSN:2198-3844
2198-3844
DOI:10.1002/advs.201970088