Efficient syntheses of multiply 2H- and 13C-labeled acrylic acid, glyceric acid, glycidic acid and glycerol

Syntheses of multiply 2H‐ and 13C‐labeled C‐3 carbohydrates have been carried out from commercially available [1,2‐13C2]bromoacetic acid. The syntheses are illustrated for [1,2‐13C2]acrylate, [2,3,3‐2H3, 1,2‐13C2]acrylate, [1,2‐13C2]glycerate, [2,3,3‐2H3, 1,2‐13C2]glycerate, [1,2‐13C2]glycidate and...

Full description

Saved in:
Bibliographic Details
Published inJournal of labelled compounds & radiopharmaceuticals Vol. 39; no. 12; pp. 999 - 1009
Main Authors Pitlik, János, Townsend, Craig A.
Format Journal Article
LanguageEnglish
Published Chichester John Wiley & Sons, Ltd 01.12.1997
Wiley
Subjects
13C) synthesis
acrylic acid
Aliphatic compounds
Chemistry
Exact sciences and technology
glyceric acid
glycerol
glycidic acid
Organic chemistry
paired isotope (2H
paired isotope (2H,13C) synthesis
Preparations and properties
Deuterium
Diol
Isotope labelling
Acrylic acid
Three membered ring
Glycerol
Hydrogen Isotopes
Oxygen heterocycle
Hydroxyacid
Epoxide
Ethylene oxide
Chemical synthesis
Carbon 13
Online AccessGet full text

Cover

More Information
Summary:Syntheses of multiply 2H‐ and 13C‐labeled C‐3 carbohydrates have been carried out from commercially available [1,2‐13C2]bromoacetic acid. The syntheses are illustrated for [1,2‐13C2]acrylate, [2,3,3‐2H3, 1,2‐13C2]acrylate, [1,2‐13C2]glycerate, [2,3,3‐2H3, 1,2‐13C2]glycerate, [1,2‐13C2]glycidate and [1,1‐2H2, 1,2‐13C2]glycerol. © 1997 John Wiley & Sons, Ltd.
Bibliography:National Institute of Health - No. RO1-AI14937; No. FO5 TW05111
ark:/67375/WNG-5JV7WR6G-L
ArticleID:JLCR45
istex:15E4146A6B4A204C55A76D23EAFD0269AF439713
ISSN:0362-4803
1099-1344
DOI:10.1002/(SICI)1099-1344(199712)39:12<999::AID-JLCR45>3.0.CO;2-Q