Study on FSHR and LHR mRNA Levels of Different BMPRIB Genotypes of Small Tail Han Sheep During the Oestrum

• Published in: Agricultural sciences in China Vol. 6; no. 1; pp. 94 - 99
• Main Authors: JIA, Cun-ling, LI, Ning, WEI, Ze-hui, ZHU, Xiao-ping, LIU, Hai-ying, JIA, Zhi-hai
• Format: Journal Article
• Language: English
• Published: College of Animal Science and Technology, China Agricultural University, Beijing 100094, P.R. China 2007; College of Animal Science and Technology, Northwest A&F University, Yangling 712100, P.R. China%National Laboratories for Agrobiotechnology, China Agricultural University, Beijing 100094, P.R. China%College of Animal Science and Technology, China Agricultural University, Beijing 100094, P.R. China
• Subjects: BMPRIB; FSHR; LHR; 信使核糖核酸; 发情期; 小尾寒羊; BMPRIB; Small Tail Han sheep; FSHR; LHR; fecundity
• ISSN: 1671-2927
• DOI: 10.1016/S1671-2927(07)60021-2

The relationship between different BMPRIB genotypes of Small Tail Han sheep and FSHR and LHR mRNA levels during the oestrum was studied using semiquantitative PCR. The results indicated that FSHR mRNA extracted from the right ovary of BB （1.14±0.11） ewes showed higher levels compared with AA （0.44±0.11） and AB （0.36±0.08） ewes （P〈0.01）, and LHR mRNA extracted from the right ovary of BB （0.42±0.02） ewes showed significantly higher levels compared with AA （0.23±0.02） and AB （0.25±0.04） ewes （P〈0.01）; however, the mRNA extracted from the left ovary showed no significant difference in levels among the genotypes during the oestrum. It indicated that the fecundity induced by a mutation of BMPRIB in Small Tail Han sheep may be related to the changes of the mRNA expression of LHR and FSHR in ovary.