A comparative study of the therapeutic effect in two protocols: video-assisted thoracic surgery combined with laparoscopy versus right open transthoracic esophagectomy for esophageal cancer management
Objective: The aim was to evaluate the best intra-thoracoscopic surgery technique between video-assisted thoracic surgery (VATS) combined with laparoscopy and right open transthoracic esophagectomy, in patients with esophageal cancer. Methods: From November 2006 to May 2008, 221 patients with esopha...
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Published in | The Chinese-German journal of clinical oncology Vol. 12; no. 2; pp. 68 - 71 |
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Main Authors | , , , , , |
Format | Journal Article |
Language | English |
Published |
Berlin/Heidelberg
Springer-Verlag
01.02.2013
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Subjects | |
Online Access | Get full text |
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Summary: | Objective: The aim was to evaluate the best intra-thoracoscopic surgery technique between video-assisted thoracic surgery (VATS) combined with laparoscopy and right open transthoracic esophagectomy, in patients with esophageal cancer. Methods: From November 2006 to May 2008, 221 patients with esophageal cancer were enrolled in this study, pro- spective randomized in two groups. 111 patients were performed the VATS technique (Experimental group), whereas in the other 110 patients esophagectomy was adopted by thoracotomy (Control group). Results: The time consuming of Experimen- tal group was 272.3 min in average with a standard deviation(std) of 57.9, and it was 218.7 min in average with std of 91.0 in the control group (P = 0.000). The operative blood loss was 219.7 ± 194.4 mL in the Experimental group, compared with 590.0 ± 324.4 mL in the control group, with significant difference (P = 0.000). Postoperative hospital stay of Experimental group was 9.6 ± 1.7 d, and it was 11.4 ± 2.3 d in the control group (P = 0.000). There was no-delayed union of incision in the Experimental group, but 6.36% in the control group (P = 0.007). The disorder of gastric emptying occurred 0.9% in the Experimental group, whereas 6.4% in the Control group. There was no significant difference in survival curves and rates (P = 0.555). Conclusion: There were several advantages of VATS technique, such as reduced hemorrhage, better recovery, few complications, and great number of lymph node dissection, although there was no significant difference in long-term survival rate. Thus the VATS combined with laparoscopy technique was worthy of generalization in esophageal surgery with good prospects. |
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Bibliography: | Objective: The aim was to evaluate the best intra-thoracoscopic surgery technique between video-assisted thoracic surgery (VATS) combined with laparoscopy and right open transthoracic esophagectomy, in patients with esophageal cancer. Methods: From November 2006 to May 2008, 221 patients with esophageal cancer were enrolled in this study, pro- spective randomized in two groups. 111 patients were performed the VATS technique (Experimental group), whereas in the other 110 patients esophagectomy was adopted by thoracotomy (Control group). Results: The time consuming of Experimen- tal group was 272.3 min in average with a standard deviation(std) of 57.9, and it was 218.7 min in average with std of 91.0 in the control group (P = 0.000). The operative blood loss was 219.7 ± 194.4 mL in the Experimental group, compared with 590.0 ± 324.4 mL in the control group, with significant difference (P = 0.000). Postoperative hospital stay of Experimental group was 9.6 ± 1.7 d, and it was 11.4 ± 2.3 d in the control group (P = 0.000). There was no-delayed union of incision in the Experimental group, but 6.36% in the control group (P = 0.007). The disorder of gastric emptying occurred 0.9% in the Experimental group, whereas 6.4% in the Control group. There was no significant difference in survival curves and rates (P = 0.555). Conclusion: There were several advantages of VATS technique, such as reduced hemorrhage, better recovery, few complications, and great number of lymph node dissection, although there was no significant difference in long-term survival rate. Thus the VATS combined with laparoscopy technique was worthy of generalization in esophageal surgery with good prospects. video-assisted thoracic surgery (VATS); laparoscopy; esophageal cancer 42-1654/R |
ISSN: | 1610-1979 1613-9089 |
DOI: | 10.1007/s10330-012-0966-0 |