Bone relapse in acute lymphoblastic leukemia

Acute lymphoblastic leukemia (ALL) can occasionally relapse in unusual extramedullary sites like bone. Here we present a 6.5-year old boy with 'T' cell ALL who developed a swelling in left tibia which was infiltrated with lymphoblasts 7 months after completion of chemotherapy. Bone marrow...

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Published inIndian journal of pediatrics Vol. 71; no. 6; pp. 555 - 557
Main Authors PADMANJALI, K. S, BAKHSHI, Sameer, THAVARAJ, Vasantha, KARAK, A. K, ARYA, L. S
Format Journal Article
LanguageEnglish
Published Heidelberg Springer 01.06.2004
Subjects
Biological and medical sciences
Bone and Bones - pathology
Child, Preschool
Hematologic and hematopoietic diseases
Humans
Leukemias. Malignant lymphomas. Malignant reticulosis. Myelofibrosis
Male
Medical sciences
Precursor Cell Lymphoblastic Leukemia-Lymphoma - pathology
Recurrence
Tibia - pathology
Asia
India
Human
Pediatrics
Relapse
Acute
Diseases of the osteoarticular system
Acute leukemia
Malignant hemopathy
Case study
Acute lymphoblastic leukemia
Lymphoproliferative syndrome
Extramedullary relapse
Tropical medicine
Acute lymphocytic leukemia
Bone
Child
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Summary:Acute lymphoblastic leukemia (ALL) can occasionally relapse in unusual extramedullary sites like bone. Here we present a 6.5-year old boy with 'T' cell ALL who developed a swelling in left tibia which was infiltrated with lymphoblasts 7 months after completion of chemotherapy. Bone marrow and cerebrospinal fluid were negative for blasts. This is the first reported case of bone relapse in ALL from India. We discuss the previous cases of isolated bone relapse in ALL reported in English literature.
Bibliography:ObjectType-Case Study-2
SourceType-Scholarly Journals-1
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ISSN:0019-5456
0973-7693
DOI:10.1007/BF02724304