Diagnostic and therapeutic challenges in PD-associated non-motor symptoms: the roles of neurologists and consultant physicians

• Published in: Journal of Neural Transmission Vol. 131; no. 10; pp. 1263 - 1273
• Main Authors: Ip, CW, Kassubek, J, Storch, A, Tönges, L, Wolz, M, Jost, WH
• Format: Journal Article
• Language: English
• Published: Vienna Springer Vienna 01.10.2024
• Subjects: Medicine; Medicine & Public Health; Neurology; Neurology and Preclinical Neurological Studies - Review Article; Neurosciences; Psychiatry; Interdisciplinary approach; Non-motor symptoms; Parkinson’s disease
• ISSN: 0300-9564; 1435-1463; 1435-1463
• DOI: 10.1007/s00702-024-02838-3

In addition to their motor symptoms, almost all Parkinson’s disease patients report non-motor symptoms (NMS) and, in the later course of the disease, non-motor fluctuations as well. These NMS encompass e.g. neuropsychiatric, gastrointestinal, urogenital, cardiovascular symptoms and pain. For a long time, these symptoms received no or at best very little attention, but there is a growing trend towards their recognition and treatment. Despite this progress, significant gaps remain, particularly due to the sometimes-limited expertise among neurologists regarding these symptoms. The clinical need to consequently treat these NMS raises the question of whether Movement Disorder specialists should and can address them sufficiently or if additional consultant physicians have to be enrolled. Therefore, our objective is to establish benchmarking criteria to outline a potential way forward. Ideally, Movement Disorder specialists should take on greater responsibility when treating non-motor PD symptoms, integrating diagnostic and therapeutic pathways from other medical disciplines where feasible.