Protein kinase Cζ: not-so-innocent bystander or unusual suspect in kidney transplant rejection?
Antibodies against non-HLA targets are increasingly recognized in the context of transplant rejection. However, their specific role remains largely elusive, as evidence exists supporting both their occurrence as an epiphenomenon and their actual pathogenicity in the rejection process. Sutherland et...
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Published in | Kidney international Vol. 76; no. 12; pp. 1223 - 1224 |
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Main Author | |
Format | Journal Article |
Language | English |
Published |
Elsevier Inc
01.12.2009
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Online Access | Get full text |
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Summary: | Antibodies against non-HLA targets are increasingly recognized in the context of transplant rejection. However, their specific role remains largely elusive, as evidence exists supporting both their occurrence as an epiphenomenon and their actual pathogenicity in the rejection process. Sutherland et al. describe protein kinase Cζ as a novel, non-HLA antigenic target in the setting of graft rejection. |
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ISSN: | 0085-2538 1523-1755 |
DOI: | 10.1038/ki.2009.393 |