A New Approach to the Synthesis of 1,2- and 1,4-Dihydropyrido[3,2-b]indole Derivatives

Intramolecular cyclization of α-cyano-β-(3-p-nitrophenylaminoindol-2-yl)acrylonitrile yields 1-p-nitrophenyl-2-imino-3-cyano-1,2-dihydropyrido[3,2-b]indole 7, methylation of which by methyl iodide in acetone in the presence of potassium carbonate is accompanied by the addition of acetonyl anion and...

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Published inMendeleev communications Vol. 5; no. 3; pp. 107 - 109
Main Authors Ryabova, Svetlana Yu, Alekseeva, Lyudmila M., Granik, Vladimir G.
Format Journal Article
LanguageEnglish
Published Elsevier B.V 1995
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Summary:Intramolecular cyclization of α-cyano-β-(3-p-nitrophenylaminoindol-2-yl)acrylonitrile yields 1-p-nitrophenyl-2-imino-3-cyano-1,2-dihydropyrido[3,2-b]indole 7, methylation of which by methyl iodide in acetone in the presence of potassium carbonate is accompanied by the addition of acetonyl anion and formation of 1-p-nitrophenyl-2-dimethylamino-3-cyano-4-acetonyl-1,4-dihydropyrido[3,2-b]indole 9.
ISSN:0959-9436
DOI:10.1070/MC1995v005n03ABEH000480