Threonyl-tRNA synthetase gene maps close to leucyl-tRNA synthetase gene on human chromosome 5

The structural gene for threonyl-tRNA synthetase was mapped to human chromosome 5 by an analysis of the isoelectric focusing patterns of this enzyme from human X Chinese hamster interspecific somatic cell hybrids. The threonyl-tRNA synthetase gene is the fourth of seven aminoacyl-tRNA synthetase gen...

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Bibliographic Details
Published inSomatic cell and molecular genetics Vol. 12; no. 5; p. 519
Main Authors Gerken, S C, Wasmuth, J J, Arfin, S M
Format Journal Article
LanguageEnglish
Published United States 01.09.1986
Subjects
Amino Acyl-tRNA Synthetases - genetics
Animals
Chromosome Mapping
Chromosomes, Human, Pair 5
Cricetinae
Genes
Genetic Linkage
Genetic Markers
Humans
Hybrid Cells
Leucine-tRNA Ligase - genetics
Threonine-tRNA Ligase - genetics
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Summary:The structural gene for threonyl-tRNA synthetase was mapped to human chromosome 5 by an analysis of the isoelectric focusing patterns of this enzyme from human X Chinese hamster interspecific somatic cell hybrids. The threonyl-tRNA synthetase gene is the fourth of seven aminoacyl-tRNA synthetase genes mapped in humans to be assigned to this chromosome. Regional mapping studies showed that the threonyl-tRNA synthetase gene is on the short arm of chromosome 5, p13-cen, and is close to, but separable from, the gene for leucyl-tRNA synthetase which maps to 5cen-5q11.
ISSN:0740-7750
1572-9931
DOI:10.1007/BF01539923