Systolic pressure target after endovascular thrombectomy in acute large‐vessel occlusion ischemic stroke patients: Comment on ENCHANTED2/MT

Elevated blood pressure during the perioperative period is associated with higher mortality and disability prevalence rates. [...]lowering post-procedure systolic pressure is a potential approach to improving patients' outcomes. [...]blood pressure is elevated in approximately 75% of patients w...

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Published inBrain-X Vol. 1; no. 1
Main Authors Yuan, Yunpeng, Wei, Baozhu, Zhu, Wenyun, Liu, Yang, Wan, Yingfeng
Format Journal Article
LanguageEnglish
Published Denton John Wiley & Sons, Inc 01.03.2023
Wiley
Subjects
Blood pressure
Clinical trials
Conflicts of interest
Hemorrhage
Hypertension
Ischemia
Mortality
Pharmacists
Stroke
Writing
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Summary:Elevated blood pressure during the perioperative period is associated with higher mortality and disability prevalence rates. [...]lowering post-procedure systolic pressure is a potential approach to improving patients' outcomes. [...]blood pressure is elevated in approximately 75% of patients with acute stroke and usually decreases spontaneously over the subsequent few days. [...]it is noteworthy that there was no difference in symptomatic intracerebral hemorrhage rates between the two groups, consistent with the previously published BP-TARGET trial, in which an aggressive systolic pressure goal of 100–129 mmHg after successful reperfusion in patients with ischemic stroke did not reduce intracerebral hemorrhage rates at 24–36 h when compared to a standard care systolic blood pressure goal of 130–185 mmHg, suggesting either a lack of protection at this level of more intensive treatment of systolic pressure or a lack of harm at this level of less intensive treatment of systolic pressure regarding symptomatic intraparenchymal hemorrhage transformation.
ISSN:2835-3153
2835-3153
DOI:10.1002/brx2.4