Expression of Cilia Structural Genes is Downregulated in Asthma and Single Nucleotide Polymorphisms in These Genes Correlate with Asthma

The levels of DNAH5, KIFC2 and KIF3A were determined by quantitative PCR using RNA derived from nasal epithelial cells from patients with stable or exacerbated asthma and RNA derived from the lungs of mice following both acute and chronic asthma models.

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Bibliographic Details
Published inJournal of allergy and clinical immunology Vol. 123; no. 2; p. S81
Main Authors Sivaprasad, U, Gibson, A.M, Wang, N, Khurana Hershey, G.K
Format Journal Article
LanguageEnglish
Published St. Louis Mosby, Inc 01.02.2009
Elsevier Limited
Subjects
Allergy and Immunology
Asthma
Genes
Medical research
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Summary:The levels of DNAH5, KIFC2 and KIF3A were determined by quantitative PCR using RNA derived from nasal epithelial cells from patients with stable or exacerbated asthma and RNA derived from the lungs of mice following both acute and chronic asthma models.
ISSN:0091-6749
1097-6825
DOI:10.1016/j.jaci.2008.12.284