Lamina Cribrosa Changes after Laser In Situ Keratomileusis in Myopic Eyes

• Published in: Korean journal of ophthalmology Vol. 32; no. 2; pp. 95 - 102
• Main Authors: Lee, Soomin, Choi, Da-Ye Diana, Lim, Dong Hui, Chung, Tae Young, Han, Jong Chul, Kee, Changwon
• Format: Journal Article
• Language: English
• Published: Korea (South) The Korean Ophthalmological Society 01.04.2018; 대한안과학회
• Subjects: Original; 안과학; Optic disk; Laser in situ keratomileusis; Lamina cribrosa
• ISSN: 1011-8942; 2092-9382; 2092-9382
• DOI: 10.3341/kjo.2017.0111

To determine deep optic nerve head structure changes after transient intraocular pressure elevation during laser in situ keratomileusis (LASIK) for myopia. Enhanced depth imaging-optical coherence tomography was performed in each myopic eye that underwent LASIK surgery. Enhanced depth imaging-optical coherence tomography images were created at postoperative 1 day, 1 week, 2 weeks, and 1 month. Lamina cribrosa (LC) thickness, LC depth and prelaminar thickness at the superior, middle and inferior portions of the optic nerve head were measured by two investigators. Forty eyes in 40 patients were included in the present study. During follow-up, there were no significant differences in prelaminar thickness or LC depth. The LC demonstrated increased thickness at postoperative 1 day at all three locations (superior, middle, and inferior) (p < 0.001, p < 0.001, p < 0.001, respectively). However, no significant changes were observed at postoperative 1 week, 2 weeks, and 1 month. The LC thickness could increase at 1 day after LASIK surgery. However, the thickness will gradually return to baseline morphology. Temporary intraocular pressure increase during LASIK does not appear to induce irreversible LC thickness changes.