Distribution of Activities of Alkaline Carboxypeptidases in Tissues of Laboratory Animals of Different Species

• Published in: Journal of evolutionary biochemistry and physiology Vol. 38; no. 1; p. 31
• Main Authors: Vernigora, A N, Shchetinina, N V, Saldaev, D A, Gengin, M T
• Format: Journal Article
• Language: English
• Published: New York Springer Nature B.V 01.01.2002
• Subjects: Laboratory animals
• ISSN: 0022-0930; 1608-3202
• DOI: 10.1023/A:1015509119612

The study deals with distribution of activities of enzymes of neuropeptide metabolism, carboxypeptidase H and phenylmethylsulfonylfluoride-inhibited carboxypeptidase (PMSF-inhibited carboxypeptidase), in tissues and organs of male cats, and breedless white rats and mice. Distribution of the carboxypeptidase H activity was very similar in different animal species, although the level of the activity differed. Essential species-specific differences in distribution of the PMSF-inhibited carboxypeptidase activity are revealed, likely due to peculiarities of metabolism of biologically active peptides and catabolism of proteins in these animal species, as well as to differences in the ratio of different isoenzymes of their PMSF-inhibited carboxypeptidase.[PUBLICATION ABSTRACT]