Pheniramine dependence: a case report

Drugs being abused may be benzodiazepines from the group of psychotropics or rarely antidepressants and antipsychotics. There are also rare cases of abuse of medicines containing ephedrine/pseudoephedrine or pheniramine, which are not only prescribed by psychiatrists. Pheniramine is an H1 histamine...

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Published inDüşünen adam (Bakırköy Ruh ve Sinir Hastalıkları Hastanesi) Vol. 32; no. 3; pp. 281 - 282
Main Author Kocamer Sahin, Sengul
Format Journal Article
LanguageEnglish
Published Istanbul Yerkure Tanitim ve Yayincilik Hizmetleri A.S 01.09.2019
Subjects
Alcohol
Case reports
Dopamine
Drug addiction
Drug therapy
Electroconvulsive therapy
Insomnia
Nervous system
Prescription drugs
Psychiatry
Psychotropic drugs
Canada
Turkey
Australia
New South Wales Australia
Quebec Canada
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Summary:Drugs being abused may be benzodiazepines from the group of psychotropics or rarely antidepressants and antipsychotics. There are also rare cases of abuse of medicines containing ephedrine/pseudoephedrine or pheniramine, which are not only prescribed by psychiatrists. Pheniramine is an H1 histamine antagonist with low sedative activity. In this article, we present a 35-year-old woman who started to use pheniramine due to depressive symptoms and insomnia but developed dependence and was hospitalized in a psychiatry clinic. According to her medical history, she had been taking venlafaxine 150mg per day for major depression for one year. The patient was treated with 7 ECT sessions combined with pharmacotherapy in our clinic for 21 days. Risks and possible mechanisms that may contribute to the development of pheniramine dependence in this patient are discussed under 3 headings: being a health care professional, self-medication of psychiatric problems, and the mechanism of action of pheniramine as an H1 histamine antagonist.
ISSN:1018-8681
1309-5749
DOI:10.14744/DAJPNS.2019.00040