Parathyroid localization in primary hyperparathyroidism: double-tracer scintigraphy and venous sampling techniques combined. A first evaluation

The authors report their first experience with two techniques for preoperative localization of hyperfunctioning parathyroid glands: double-tracer (99mTc-201Tl) scintigraphy and venous sampling from thyroid veins. Nineteen patients affected by primary hyperparathyroidism were examined by both methods...

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Bibliographic Details
Published inJournal of endocrinological investigation Vol. 7; no. 4; p. 363
Main Authors Zotti, D, Borsato, N, Varotto, S, Miotto, D, Feltrin, G P, Tasca, A, Ferlin, G, Lumachi, F, Pacelli, P, D'Erminio, A
Format Journal Article
LanguageEnglish
Published Italy 01.08.1984
Subjects
Adenoma - surgery
Carcinoma - surgery
Humans
Hyperparathyroidism - diagnostic imaging
Hyperparathyroidism - surgery
Hyperplasia - surgery
Parathyroid Glands - diagnostic imaging
Parathyroid Glands - pathology
Parathyroid Neoplasms - surgery
Radioisotopes
Radionuclide Imaging
Technetium
Thallium
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Summary:The authors report their first experience with two techniques for preoperative localization of hyperfunctioning parathyroid glands: double-tracer (99mTc-201Tl) scintigraphy and venous sampling from thyroid veins. Nineteen patients affected by primary hyperparathyroidism were examined by both methods and subsequently submitted to surgery. Scintigraphy showed a sensitivity of 77.3% while the positivity of sampling was 63.6%; with the two techniques combined a correct localization was obtained in 90.9% of all cases. The authors emphasize the usefulness of both methods combined for locating enlarged hyperfunctioning parathyroids.
ISSN:0391-4097
DOI:10.1007/BF03351017