Antifungal Activity of Alkaloids Against Candida albicans

Candida albicans is a pathogen in the mouth responsible for opportunistic infections that are usually harmless. Natural products have been used to develop several drugs, mostly anticancer and anti-infective agents. Among these, alkaloids have been studied for their medicinal properties. In this stud...

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Bibliographic Details
Published inJournal of the California Dental Association Vol. 44; no. 8; pp. 493 - 498
Main Authors Noguti, Juliana, Rajinia, Mersedeh, Zancope, Bruna Raquel, Marquezin, Maria Carolina Salome, Seleem, Dalia, Pardi, Vanessa, Murata, Ramiro M
Format Journal Article
LanguageEnglish
Published United States 01.08.2016
Subjects
Alkaloids - pharmacology
Antifungal Agents - pharmacology
Candida albicans - drug effects
Dentistry
Humans
Microbial Sensitivity Tests
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Summary:Candida albicans is a pathogen in the mouth responsible for opportunistic infections that are usually harmless. Natural products have been used to develop several drugs, mostly anticancer and anti-infective agents. Among these, alkaloids have been studied for their medicinal properties. In this study, we examined their antifungal activity against C. albicans in vitro. Among the alkaloids studied in this work, berberine hydrochloride showed the best activity against C. albicans.
Bibliography:ObjectType-Article-1
SourceType-Scholarly Journals-1
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ISSN:1043-2256
1942-4396
1942-4396
DOI:10.1080/19424396.2016.12221046