Smart controlled-release nanopesticides based on metal-organic frameworks
The practical utilization rates of conventional pesticide formulations by target organisms are very low, which results in the pollution of ecological environments and the formation of pesticide residues in agricultural products. Water-based nanopesticide formulations could become alternative and eff...
Saved in:
| Published in | Chemical communications (Cambridge, England) Vol. 6; no. 48; pp. 682 - 692 |
|---|---|
| Main Authors | , , , |
| Format | Journal Article |
| Language | English |
| Published |
England
Royal Society of Chemistry
11.06.2024
|
| Subjects | |
| Online Access | Get full text |
Cover
Loading…
| Summary: | The practical utilization rates of conventional pesticide formulations by target organisms are very low, which results in the pollution of ecological environments and the formation of pesticide residues in agricultural products. Water-based nanopesticide formulations could become alternative and effective formulations to eventually resolve the main issues of conventional pesticide formulations. In this feature article, we describe the design concept of smart (stimuli-responsive) controlled-release nanopesticides, which are created toward hierarchical targets (pests, pathogens, and foliage) in response to multidimensional stimuli from physiological and environmental factors (such as sunlight) of target organisms and plants, for achieving enhanced insecticidal and fungicidal efficacies. The pore sizes and functionalities of metal-organic frameworks (MOFs) can be fine-tuned through the choice of metal-containing units and organic ligands. Tailor-made MOF nanoparticles with large microporous or mesoporous sizes, as well as good biocompatibility and high thermal, mechanical, and chemical durabilities, are used to load pesticides within these pores followed by coating of plant polyphenols and natural polymers for stimuli-responsive controlled pesticide release. This feature article highlights our works on smart controlled-release MOF-based nanopesticides and also includes related works from other laboratories. The future challenges and promising prospects of smart controlled-release MOF-based nanopesticides are also discussed.
Recent progress in smart controlled-release nanopesticides based on metal-organic frameworks toward hierarchical targets in response to multidimensional stimuli is highlighted to enhance pesticide efficacy. |
|---|---|
| Bibliography: | Xin Jin received his bachelor's degree in pharmacy from Huanghe Science & Technology University, China, in 2019 and M.Med degree in pharmacy from Henan University, China, in 2022. He is currently a PhD candidate at the School of Chemistry and Chemical Engineering, Nanjing University, China, under the supervision of Prof. Xuezhong Du. His current research interests focus on stimuli-responsive drug/pesticide delivery based on metal-organic frameworks. Ruixi Xiao received her bachelor's degree in light chemical engineering from East China University of Science and Technology, China, in 2022. She is currently a postgraduate student at the School of Chemistry and Chemical Engineering, Nanjing University, China, under the supervision of Prof. Xuezhong Du. Her current research interests focus on controlled-release nanopesticides. Xuezhong Du received his PhD degree in chemistry from Nanjing University, China, in 1998. He moved to Dalian Institute of Chemical Physics, Chinese Academy of Sciences, during 1999 to 2000 and the Department of Bioengineering, The University of Utah, USA, during 2000 to 2002, respectively, as a postdoctoral research fellow. Since 2002, he has been a professor of chemistry at the School of Chemistry and Chemical Engineering, Nanjing University. His current research interests focus on controlled self-assembly and stimuli-responsive drug delivery including nanomedicine (since 2007) and nanopesticides (since 2017). Zejun Cao received his bachelor's degree in applied chemistry from China University of Petroleum (East China), China, in 2022. He is currently a postgraduate student at the School of Chemistry and Chemical Engineering, Nanjing University, China, under the supervision of Prof. Xuezhong Du. His current research interests focus on controlled-release nanopesticides. ObjectType-Article-2 SourceType-Scholarly Journals-1 ObjectType-Feature-3 content type line 23 ObjectType-Review-1 |
| ISSN: | 1359-7345 1364-548X |
| DOI: | 10.1039/d4cc01390e |