Allergic Rhinitis: Natural History. A Twenty Years Follow up Study

• Published in: European journal of inflammation Vol. 1; no. 1; pp. 17 - 23
• Main Authors: Passàli, D., Damiani, V., Passàli, G.C., Passàli, F.M., Bellussi, L.
• Format: Journal Article
• Language: English
• Published: London, England SAGE Publications 01.01.2003; SAGE PUBLICATIONS, INC; SAGE Publishing
• Subjects: Asthma; Histamine; Immunotherapy; Nose; allergens exposition; asthma; allergic rhinitis; symptomatic drugs; immunotherapy
• ISSN: 2058-7392; 1721-727X; 2058-7392
• DOI: 10.1177/1721727X0300100105

Although there is an agreement on the increase of the prevalence of allergic rhinitis in last decades, data emerging from various studies appear to be widely dishomogeneous. Another point that needs a clarification is the relationship between allergic rhinitis and lower airways pathologies such as asthma or bronchitis. In this study, we followed the evolution of allergic rhinitis in a group of patients in the last 20 years to highlight the efficacy of different treatments in the prevention of complications, specifically asthma. Patients who didn't receive any kind of treatment experimented a remission of symptoms in 4 cases, a stability of the disease in 6 and the development of complications in 11. In the group treated with symptomatic drugs we highlighted a recovery in 11 patients, a stability of symptoms in 2 and complications in 2. At last, patients undergone immunotherapy considered their symptoms improved in 60 % and stable in 40 % of cases. In conclusion, Immunotherapy guarantees, in a large number of patients, remission of local symptoms and valid protection against district and bronchial complications. Symptomatic treatment with antihistamines and/or cortisones represents a valid alternative, and it's always to be preferred to abstention from any treatment.