Langerhans cell histiocytosis in adults: literature review

Langerhans cells histiocytosis is a variant of malignant histiocytosis. The course and symptoms vary. patients with localized forms have a better prognosis, because local therapy is effective. patients with multifocal forms of histiocytosis receive systemic drug therapy, which cures some of the pati...

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Bibliographic Details
Published inOnkogematologii͡a Vol. 17; no. 4; pp. 16 - 32
Main Authors Potapenko, V. G., Baykov, V. V., Zinchenko, A. V., Potikhonova, N. A.
Format Journal Article
LanguageEnglish
Published ABV-press 03.11.2022
Subjects
braf
cladribine
cobimetinib
diabetes insipidus
langerhans cell histiocytosis
mapk
mek
pneumothorax
vemurafenib
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Summary:Langerhans cells histiocytosis is a variant of malignant histiocytosis. The course and symptoms vary. patients with localized forms have a better prognosis, because local therapy is effective. patients with multifocal forms of histiocytosis receive systemic drug therapy, which cures some of the patients. This review provides up-to-date data about typical presentation of the organ involvement, diagnosis, course and therapy of various forms of Langerhans cells histiocytosis.
ISSN:1818-8346
2413-4023
DOI:10.17650/1818-8346-2022-17-4-16-32