The use of the level of evidence and grade of recommendations scales in developing clinical guidelines in the Russian Federation

• Published in: Farmakoèkonomika (Moskva. Online) Vol. 12; no. 1; pp. 34 - 41
• Main Authors: Zhuravleva, N. I., Shubina, L. C., Sukhorukikh, O. A.
• Format: Journal Article
• Language: English; Russian
• Published: IRBIS LLC 23.05.2019
• Subjects: clinical guidelines; evidence-based medicine; grade of recommendation; level of evidence
• ISSN: 2070-4909; 2070-4933
• DOI: 10.17749/2070-4909.2019.12.1.34-41

Aim – analyze the existing systems for assessing the levels of evidence (LE-scales) and grades of recommendation (GR-scales) in the development of clinical guidelines in the Russian Federation. Materials and Methods. We analyzed the LE- and GR-scales that had been used in developing clinical guidelines up to 01.09.2017; the materials were stored in the Federal Electronic Medical Library. The study included several stages: analysis of the clinical guidelines for the presence and type of LE- and GR-scales; comparison of the LE- and GR-scales between various clinical guidelines including the internationally accepted ones; assessment of using the international scales or their combinations in the development of clinical guidelines in Russia. Results. More than 150 various LE- and GR-scales used for clinical recommendations were identified; most of them represented modifications of the international assessment systems. The original SIGN technique was found to be most commonly used. Conclusion. Based on the results of the study, we concluded that at present, there is no unified approach to the assessment of the levels of evidence and grades of recommendation in clinical guidelines developed by professional medical associations in the Russian Federation.