A Case of Antimitochondrial Antibody Negative Primary Biliary Cirrhosis from Bangladesh and Review of Literature

Primary biliary cirrhosis (PBC) is very closely associated with the presence of antimitochondrial antibodies (AMA). Nevertheless, 5 to 10% of patients with typical features of primary biliary cirrhosis do not have detectable AMA. They are referred to as AMA negative PBC. We report a case of PBC who...

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Published inEuroasian journal of hepato-gastroenterology Vol. 5; no. 2; pp. 122 - 126
Main Authors Begum, Roksana, Mahtab, Mamun-Al, Al Mamun, Ayub, Kumar Saha, Biplob, Shahadat Hossain, Sharker Mohammad, Chandra Das, Dulal, Fazle Akbar, Sheikh Mohammad, Kamal, Mohammad, Rahman, Salimur
Format Journal Article
LanguageEnglish
Published India Jaypee Brothers Medical Publishers 01.07.2015
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Summary:Primary biliary cirrhosis (PBC) is very closely associated with the presence of antimitochondrial antibodies (AMA). Nevertheless, 5 to 10% of patients with typical features of primary biliary cirrhosis do not have detectable AMA. They are referred to as AMA negative PBC. We report a case of PBC who was AMA-negative. The patient was a middle-aged woman seeking help of dermatologist for her complaint of itching. The diagnosis was confirmed by histopathology, whereas other possible causes of cirrhosis were excluded. Begum R, Mahtab MA, Mamun AA, Saha BK, Hossain SMS, Saha DC, Akbar SMF, Kamal M, Rahman S. A Case of Antimitochondrial Antibody Negative Primary Biliary Cirrhosis from Bangladesh and Review of Literature. Euroasian J Hepato-Gastroenterol 2015;5(2):122-126.
ISSN:2231-5047
2231-5128
DOI:10.5005/jp-journals-10018-1150