The use of hydrazones for efficient mannich type coupling with aldehydes and secondary amines

• Published in: Chemical communications (Cambridge, England) no. 17; pp. 1585 - 1586
• Main Authors: Atlan, Bienayme, H, El Kaim, L, Majee, A
• Format: Journal Article
• Language: English
• Published: CAMBRIDGE Royal Soc Chemistry 01.01.2000
• Subjects: Chemistry; Chemistry, Multidisciplinary; Physical Sciences; Science & Technology

The Mannich reaction of hydrazones originally limited to the coupling of hydrazones with formaldehyde has been extended to a large variety of aldehydes through appropriate selection of experimental conditions; in conjunction with the Japp-Klingmann reaction, this process provides an efficient synthe...