The use of hydrazones for efficient mannich type coupling with aldehydes and secondary amines
The Mannich reaction of hydrazones originally limited to the coupling of hydrazones with formaldehyde has been extended to a large variety of aldehydes through appropriate selection of experimental conditions; in conjunction with the Japp-Klingmann reaction, this process provides an efficient synthe...
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Published in | Chemical communications (Cambridge, England) no. 17; pp. 1585 - 1586 |
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Main Authors | , , , |
Format | Journal Article |
Language | English |
Published |
CAMBRIDGE
Royal Soc Chemistry
01.01.2000
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Subjects | |
Online Access | Get full text |
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Summary: | The Mannich reaction of hydrazones originally limited to the coupling of hydrazones with formaldehyde has been extended to a large variety of aldehydes through appropriate selection of experimental conditions; in conjunction with the Japp-Klingmann reaction, this process provides an efficient synthetic tool for the formation of carbon-carbon bonds. |
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ISSN: | 1359-7345 1364-548X |
DOI: | 10.1039/b002750m |