The use of hydrazones for efficient mannich type coupling with aldehydes and secondary amines
The Mannich reaction of hydrazones originally limited to the coupling of hydrazones with formaldehyde has been extended to a large variety of aldehydes through appropriate selection of experimental conditions; in conjunction with the Japp-Klingmann reaction, this process provides an efficient synthe...
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Published in | Chemical communications (Cambridge, England) no. 17; pp. 1585 - 1586 |
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Main Authors | , , , |
Format | Journal Article |
Language | English |
Published |
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Royal Soc Chemistry
01.01.2000
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Abstract | The Mannich reaction of hydrazones originally limited to the coupling of hydrazones with formaldehyde has been extended to a large variety of aldehydes through appropriate selection of experimental conditions; in conjunction with the Japp-Klingmann reaction, this process provides an efficient synthetic tool for the formation of carbon-carbon bonds. |
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AbstractList | The Mannich reaction of hydrazones originally limited to the coupling of hydrazones with formaldehyde has been extended to a large variety of aldehydes through appropriate selection of experimental conditions; in conjunction with the Japp-Klingmann reaction, this process provides an efficient synthetic tool for the formation of carbon-carbon bonds. |
Author | Majee, A Atlan El Kaim, L Bienayme, H |
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References | SEEBACH, D (WOS:A1984TK76500025) 1984; 67 KLEINMAN EF (WOS:000088914800013.3) 1991; 2 Attanasi, OA (WOS:A1997YG33000002) 1997 RIED, W (WOS:A1957WU15600020) 1957; 605 Yamada, K (WOS:000084141900018) 1999; 38 |
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Snippet | The Mannich reaction of hydrazones originally limited to the coupling of hydrazones with formaldehyde has been extended to a large variety of aldehydes through... |
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Title | The use of hydrazones for efficient mannich type coupling with aldehydes and secondary amines |
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