Investigation of the relationship between upper limb apraxia and neuropsychological profile in Alzheimer’s disease dementia and mild cognitive impairment

Objectives: This study aimed to examine the differences in upper limb apraxia assessments and neuropsychological profiles of patients diagnosed with Alzheimer’s disease (AD) dementia and mild cognitive impairment (MCI) and healthy controls. Patients and methods: A total of 53 participants were inclu...

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Bibliographic Details
Published inTürk nöroloji dergisi Vol. 30; no. 2; pp. 93 - 101
Main Authors Sahinturk, Saliha, Doganoglu, Irem, Hanoglu, Lutfu, Yildirim, Erol
Format Journal Article
LanguageEnglish
Published Galenos Yayinevi Tic. Ltd 01.06.2024
Subjects
Advertising executives
Alzheimer's disease
Apraxia
Arm
Cognition disorders
Complications and side effects
Diagnosis
Diseases
Extremities, Upper
Health aspects
Investigations
Medical research
Medicine, Experimental
Neuropsychological tests
Physiological aspects
Risk factors
Turkey
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Summary:Objectives: This study aimed to examine the differences in upper limb apraxia assessments and neuropsychological profiles of patients diagnosed with Alzheimer’s disease (AD) dementia and mild cognitive impairment (MCI) and healthy controls. Patients and methods: A total of 53 participants were included in the retrospective study, including nine patients with MCI, 23 patients diagnosed with AD, and 21 healthy patients equivalent in age and education level. The participants’ data were collected between July 2021 and December 2022. A 12-question mini-test taken from the Test of Upper Limb Apraxia (TULIA) was used in the apraxia evaluation. Individuals’ upper limb apraxia evaluations were compared according to diagnostic groups, and their neuropsychological profiles were also examined. Results: Apraxia was found to be associated with impairments in memory retrieval function, executive dysfunction, and decrease in object naming performance. Significant differences were observed between diagnostic groups in both apraxia assessment and neuropsychological tests. Conclusion: The findings indicate that the cognitive profile that emerges with the combined use of upper extremity apraxia assessment and related neuropsychological tests may serve as a marker and guide in the planning and correct execution of treatment in the transition to Alzheimer-type dementia, similar to other neuropsychological tests.
ISSN:1309-2545
1301-062X
1309-2545
DOI:10.55697/tnd.2024.4