Correlation between CD4^＋CD25^＋Treg Cells and CCR4 in Nasopharyngeal Carcinoma

• Published in: Cancer biology & medicine Vol. 8; no. 2; pp. 106 - 113
• Main Authors: Ren, Yan-xin, Sui, Jun, Song, Xin, Wan Wong, Gee, Ma, Jing, Yao, Hong, Lin, Marie Chia-mi, Li, Xiao-jiang
• Format: Journal Article
• Language: English
• Published: Heidelberg Tianjin Medical University Cancer Institute and Hospital 01.06.2011; China Anti-Cancer Association
• Subjects: CCR4; CD4; CD4+CD25+ Treg cells; eg细胞; flow cytometry; Medicine; Medicine & Public Health; nasopharyngeal carcinoma; Oncology; tumor-infiltrating lymphocytes; 免疫系统; 淋巴细胞; 肿瘤浸润; 调节性T细胞; 趋化因子受体; 鼻咽癌; nasopharyngeal carcinoma; CD4; cells; T; tumor-infiltrating lymphocytes; flow cytometry; CD25; CCR4

OBJECTIVE CD4^＋CD25^＋ T regulatory （Treg） cells are a population of T cells which suppress an overactive immune system. CCR4 is a chemokine receptor involved in the recruitment of lymphocytes. Nasopharyngeal carcinoma （NPC） is resistant to immunosurveillance, owing to the increased number of tumor-i...