Stereospecific ligands and their complexes, Part VIII: Antimicrobial activity of palladium(II) complexes with 0,0'-dialkyl esters of (S,S)-ethylenediamine-N,N'-di-2-(4-methyl)-pentanoic acid
Palladium(II) complexes (1-4) of general formula [PdCl2(R2-S,S-eddp)] with bidentate N,N?-ligands, O,O'-dialkyl esters (R = ethyl, n-propyl, n-butyl and n-pentyl), of (S,S)-ethylenediamine-N,N?-di-2-(4-methyl)pentanoic acid (S,S-eddp) were prepared and characterized by microanalysis, infrared a...
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Published in | Hemijska industrija Vol. 66; no. 3; pp. 349 - 355 |
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Main Authors | , , , , , , |
Format | Journal Article |
Language | English Serbian |
Published |
Belgrade
Hemijska Industrija
2012
Association of Chemical Engineers of Serbia |
Subjects | |
Online Access | Get full text |
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Summary: | Palladium(II) complexes (1-4) of general formula [PdCl2(R2-S,S-eddp)] with
bidentate N,N?-ligands, O,O'-dialkyl esters (R = ethyl, n-propyl, n-butyl and
n-pentyl), of (S,S)-ethylenediamine-N,N?-di-2-(4-methyl)pentanoic acid
(S,S-eddp) were prepared and characterized by microanalysis, infrared and
UV/VIS spectroscopy. The ligands and its complexes were tested for their in
vitro antimicrobial activity against 15 species of bacteria and fungi.
Testing is performed by the microdilution method, with the minimum inhibitory
concentration (MIC) and the minimum microbicidal concentration (MMC) being
determined. The MIC values were in range from 4.9 ?g cm-3 to > 5000 ?g cm-3
while MMC values ranged from 78 ?g cm-3 to > 5000 ?g cm-3. Palladium(II)
complexes [PdCl2(Ln)] (n = 1-4) have statistically significant higher
activity than the corresponding ligands. The complex 4 displayed the
strongest activity among all tested compounds.
nema |
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ISSN: | 0367-598X 2217-7426 |
DOI: | 10.2298/HEMIND110928096I |