A case of advanced oral undifferentiated carcinoma successfully treated by concomitant chemoradiotherapy

• Published in: Journal of Japanese Society of Oral Oncology Vol. 7; no. 1; pp. 15 - 20
• Main Authors: Shindo, Junichi, Kamata, Hitoshi, Akasaka, Yoko, Watanabe, Yoshihisa, Jinbu, Yoshinori, Takagi, Shinobu
• Format: Journal Article
• Language: Japanese
• Published: Japanese Society of Oral Oncology 1995
• Subjects: concomitant chemoradiotherapy; oral cancer; quality of life (QOL); undifferentiated carcinoma
• ISSN: 0915-5988; 1884-4995
• DOI: 10.5843/jsot.7.15

We experienced an advanced case of oral undifferentiated carcinoma which was widely spread from lower lip to the entire region of lower gingiva and floor of mouth. The patient was a 50-year-old male who complained of gingival retraction and pain at lower frontal teeth. There were no abnormal findings in panoramic tomograph and CT, however, Tc-99m MDP accumulation was observed at the mandible in bone scintigraphy and Ga-67 accumulation at the region of both side of cervical lymph nodes in Ga-67 scintigraphy. Histopathological examination showed an undifferentiated carcinoma. The patient was successfully treated by concomitant chemo-radiotherapy (PEP : 120mg, 60Co : 49.9 Gy), and the shape and function of the mouth was completely preserved. There have been no recurrences at least 1 year and 6 months after treatment.