Mycobacterium Tuberculosis Infection in AECOPD Combined with Pulmonary Embolism: a Case Report

• Published in: Clinical laboratory (Heidelberg) Vol. 69; no. 4
• Main Authors: Bai, Jing S, Zhang, Qin, Liu, Jing X, Wang, Jing M, Chen, Qian C, Zhou, Xin Y, Liu, Rong X, Gao, Shan, Fu, Ai S, Ge, Yan L
• Format: Journal Article
• Language: English
• Published: Germany 01.04.2023
• Subjects: Antacids; Dyspnea; Humans; Mycobacterium tuberculosis; Pulmonary Disease, Chronic Obstructive; Pulmonary Embolism - complications; Pulmonary Embolism - diagnosis; Tuberculosis; Tuberculosis, Pulmonary - complications; Tuberculosis, Pulmonary - diagnosis; Tuberculosis, Pulmonary - microbiology
• ISSN: 1433-6510
• DOI: 10.7754/Clin.Lab.2022.220815

Mycobacterium tuberculosis belongs to the group of mycobacteria, most of which can cause a delayed hypersensitivity reaction in the body and is a bacterium that causes tuberculosis. Mycobacterium tuberculosis infection often presents with symptoms of tuberculosis toxicity and rarely with respiratory distress. At the same time, chest imaging often shows an ill-defined solid shadow in the apical and posterior segments of the upper lobe and, less frequently, in the dorsal segment of the lower lobe, and less frequently a diffuse nodular shadow. We report a case of AECOPD combined with pulmonary embolism infected with Mycobacterium tuberculosis. Bronchoscopy, Next-generation sequencing (NGS). Antacid staining of bronchoalveolar lavage fluid suggested that a small amount of Mycobacterium antacid was visible. NGS was sent for examination and it suggested the presence of Mycobacterium tuberculosis with a sequence number of 5 (reference range ≥ 0). Treatment such as bronchodilation and antituberculosis was given. In patients with dyspnea, it is crucial to find the causative agent and to promptly improve relevant examinations such as pulmonary arteriography and bronchoscopy, and if necessary, to make a definitive diagnosis by NGS.