Toll-like Receptor 4 Signaling Pathway Mediates Inhalant Organic Dust-Induced Bone Loss

Because Toll-like receptor 2 (TLR2) and TLR4 are important in mediating the airway consequences of ODE, we sought to determine effects on systemic bone responses.

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Bibliographic Details
Published inJournal of allergy and clinical immunology Vol. 137; no. 2; p. AB175
Main Authors Poole, Jill A., MD, FAAAAI, Klein, Elizabeth, Dusad, Anand, MD, Wyatt, Todd, PhD, Romberger, Debra, MD, Duryee, Michael, Klassen, Lynell, MD, Mikuls, Ted, MD, Wang, Dong, PhD, Thiele, Geoffrey, PhD
Format Journal Article
LanguageEnglish
Published St. Louis Elsevier Inc 01.02.2016
Elsevier Limited
Subjects
Allergy and Immunology
Bone marrow
Rodents
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Summary:Because Toll-like receptor 2 (TLR2) and TLR4 are important in mediating the airway consequences of ODE, we sought to determine effects on systemic bone responses.
ISSN:0091-6749
1097-6825
DOI:10.1016/j.jaci.2015.12.708