Biotin studies in pigs

Eight pigs were given a semi-purified diet based on maize flour and casein containing 10 μg biotin/kg. The diet was given ad lib. with or without a supplement of 70 μg biotin/kg diet from 5 to 94 d of age. The flow of biotin in the stomach was similar to the biotin intake (13.5 and 112 μg/d) for the...

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Bibliographic Details
Published inBritish journal of nutrition Vol. 62; no. 3; pp. 767 - 772
Main Authors Kopinski, J. S., Leibholz, Jane, Bryden, W. L.
Format Journal Article
LanguageEnglish
Published Cambridge, UK Cambridge University Press 01.11.1989
Subjects
Biotin synthesis
Pig
Vitamins
Biotin synthesis
Pig
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Summary:Eight pigs were given a semi-purified diet based on maize flour and casein containing 10 μg biotin/kg. The diet was given ad lib. with or without a supplement of 70 μg biotin/kg diet from 5 to 94 d of age. The flow of biotin in the stomach was similar to the biotin intake (13.5 and 112 μg/d) for the unsupplemented and biotin-supplemented pigs respectively. The flow of biotin through the small intestine decreased for the biotin-supplemented pigs from 39 μg/d in the first quarter of the small intestine to 7.9 μg/d in the last quarter. The flows of biotin in the caecum, large intestine and colon were similar for both the unsupplemented and biotin-supplemented pigs, with values of 17–54 μg/d, indicating the synthesis of biotin in the hind-gut.
Bibliography:For reprints.
PII:S0007114589001601
istex:E606602DD04717974319313B54C577EC9B15C5FF
ArticleID:00160
ark:/67375/6GQ-4647JH0J-0
ISSN:0007-1145
1475-2662
DOI:10.1079/BJN19890077