Approximation of Splenic NK and Dendritic Cells in Perforin-Deficient Hemophagocytic Syndrome: Insights into Pathogenesis

Natural killer cell function, perforin flow cytometry as well as lymphoid tissue immunohistologic analysis of NK cells, T cells, dendritic cells (DC) and macrophages during acute fatal human HLH was performed.

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Bibliographic Details
Published inJournal of allergy and clinical immunology Vol. 127; no. 2; p. AB90
Main Authors Keller, M.D, Paessler, M.E, Orange, J
Format Journal Article
LanguageEnglish
Published St. Louis Mosby, Inc 01.02.2011
Elsevier Limited
Subjects
Allergy and Immunology
Cytotoxicity
Immune system
Pathogenesis
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Summary:Natural killer cell function, perforin flow cytometry as well as lymphoid tissue immunohistologic analysis of NK cells, T cells, dendritic cells (DC) and macrophages during acute fatal human HLH was performed.
ISSN:0091-6749
1097-6825
DOI:10.1016/j.jaci.2010.12.362