A Rationally Designed Microbial Consortium Attenuates Allergic Asthma in a Murine Model

Results Supplementation with the microbial consortium and L. johnsoniicombined provided the most robust protection against allergic asthma, including significant decreases in lung mucin hyperplasia and Muc5 gene expression, as well as decreases in Th2-related cytokines.

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Bibliographic Details
Published inJournal of allergy and clinical immunology Vol. 137; no. 2; p. AB97
Main Authors Kimes, Nikole E., PhD, Valladares, Ricardo B., PhD, Lin, Din L., PhD, Lynch, Susan V., PhD
Format Journal Article
LanguageEnglish
Published St. Louis Elsevier Inc 01.02.2016
Elsevier Limited
Subjects
Allergies
Allergy and Immunology
Asthma
Gene expression
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Summary:Results Supplementation with the microbial consortium and L. johnsoniicombined provided the most robust protection against allergic asthma, including significant decreases in lung mucin hyperplasia and Muc5 gene expression, as well as decreases in Th2-related cytokines.
ISSN:0091-6749
1097-6825
DOI:10.1016/j.jaci.2015.12.442