Expression of Cyclooxygenase-2 in Ovarian Cancer Cell Lines

Summary： To investigate the expression of cyclooxygenase-2 （COX-2） in ovarian cancer cell lines, RT-PCR and immunocytochemistry were used to detect the expression of COX-2 in 5 ovarian cancer cell lines. The expression of COX-2 mRNA and protein was detected in all 5 cell lines. It is suggested that...

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Published inJournal of Huazhong University of Science and Technology. Medical sciences Vol. 25; no. 5; pp. 536 - 537
Main Author 李晓艳 董卫红 王泽华
Format Journal Article
LanguageEnglish
Published China Department of Obstetrics and Gynecology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022, China 2005
Subjects
Cell Line, Tumor
Cyclooxygenase 2 - genetics
Cyclooxygenase 2 - metabolism
Female
Humans
Ovarian Neoplasms - enzymology
Ovarian Neoplasms - pathology
RNA, Messenger - genetics
RNA, Messenger - metabolism
卵巢肿瘤
基因表达
环氧合酶-2
肿瘤细胞
ovarian cancer
cell lines
cyclooxygenase-2
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Summary:Summary： To investigate the expression of cyclooxygenase-2 （COX-2） in ovarian cancer cell lines, RT-PCR and immunocytochemistry were used to detect the expression of COX-2 in 5 ovarian cancer cell lines. The expression of COX-2 mRNA and protein was detected in all 5 cell lines. It is suggested that COX-2 is expressed in ovarian cancer cell lines, which provides a Basis for the chemoprevention of ovarian cancer.
Bibliography:R737.31
42-1679/R
ovarian cancer
cell lines
ovarian cancer; cell lines; cyclooxygenase-2
cyclooxygenase-2
ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
content type line 23
ISSN:1672-0733
1993-1352
DOI:10.1007/bf02896010