Research progress on measurement methods and evaluation of the hemodialysis adequacy index Kt/V

• Published in: Therapeutic apheresis and dialysis
• Main Authors: Li, Le-le, Xu, Rui-Feng, He, Ning, Hu, Ta-la, Gao, Wu-Niri, Wang, Xi-Feng, Shi, Dong-Ying, Zhao, Jian-Rong, Meng, Yan
• Format: Journal Article
• Language: English
• Published: Australia 10.10.2024
• Subjects: end‐stage renal disease (ESRD); urea removal index (Kt/V); chronic kidney disease (CKD); dialysis adequacy; maintenance hemodialysis (MHD)
• ISSN: 1744-9979; 1744-9987; 1744-9987
• DOI: 10.1111/1744-9987.14217

The most common form of replacement therapy for end-stage renal disease (ESRD) is hemodialysis, and the adequacy of hemodialysis is strongly associated with the quality of life and long-term survival of patients. Kt/V is currently one of the most important indicators for evaluating the adequacy of hemodialysis. There are many methods for measuring Kt/V, such as blood collection and measurement, dialysate measurement, bioresistive resistance, WinNonlin software analysis, and artificial intelligence. There are different views on the importance of Kt/V as an indicator of the adequacy of hemodialysis. This article provides a literature review of the various methods of measuring Kt/V and on different perspectives on Kt/V as an evaluation of hemodialysis adequacy.