Diabetic Markers, Five Years after Bariatric Surgery

• Published in: Middle East journal of digestive diseases Vol. 15; no. 4; pp. 270 - 276
• Main Authors: Behrooznia, Zahra, Jangjoo, Ali, Qoorchi Moheb Seraj, Farid, Khadem-Rezaiyan, Majid, Zandbaf, Tooraj, Hassani, Solmaz
• Format: Journal Article
• Language: English
• Published: Iran Iranian Association of Gastroerterology and Hepatology 01.10.2023
• Subjects: Original; R-Y gastric bypass; Morbid obesity; Diabetes mellitus; One anastomosis single bypass; Bariatric surgery; Sleeve gastrectomy
• ISSN: 2008-5230; 2008-5249
• DOI: 10.34172/mejdd.2023.357

Bariatric surgery delivers substantial weight loss for obese patients with comorbidities like diabetes mellitus. We aimed to investigate the impacts of bariatric surgery on diabetic markers after 5 years of follow-up. This is a retrospective study on patients with diabetes and a history of bariatric surgery between 2016-2017. The diabetic markers before and 5 years following surgery, including a lipid profile, glucose level, and the required antidiabetic medications, were evaluated. 34 consecutive patients were included, 30 (88.2%) women, with a mean age of 52.71±8.53 years. The majority (65%) of surgeries were Roux-en-Y gastric bypass (RYGB), and the remaining were one anastomosis gastric bypass (OAGB) and sleeve gastrectomy (SG). The serum levels of diabetic markers reduced during follow-up ( =0.001), except for high-density lipoprotein levels and serum total cholesterol, which increased ( =0.011, =0.838). Low-density lipoprotein levels reduced, but it was insignificant ( =0.194). Surgery types had affected the changes of diabetic markers ( >0.05). Demand for oral medication was reduced significantly, but insulin injection reduction was not significant ( =0.006 and =0.099, respectively). Our study showed favorable bariatric surgery results on patients with diabetes in long-term follow-up. However, dyslipidemia is still a concern.