Synthesis of 7,7′-bisindolizines by the reaction of 4,4′-bipyridinium-ylides with activated alkynes

Eight new bis-indolizine heterocycles were prepared. We have accomplished a theoretical and experimental study looking at the regiochemistry of 3+2 dipolar cycloadditions of 4,4′-bipyridinium ylides (6–10) 1,2 to ethyl propiolate and dimethyl acetylenedicarboxylate. The synthesis of indolizines (1)...

Full description

Saved in:
Bibliographic Details
Published inTetrahedron Vol. 54; no. 36; pp. 10811 - 10818
Main Authors Druta, Ioan I., Dinica, Rodica M., Bacu, Elena, Humelnicu, I.
Format Journal Article
LanguageEnglish
Published Elsevier Ltd 03.09.1998
Online AccessGet full text

Cover

More Information
Summary:Eight new bis-indolizine heterocycles were prepared. We have accomplished a theoretical and experimental study looking at the regiochemistry of 3+2 dipolar cycloadditions of 4,4′-bipyridinium ylides (6–10) 1,2 to ethyl propiolate and dimethyl acetylenedicarboxylate. The synthesis of indolizines (1) by the cycloaddition reactions of 4,4′-bipyridinium ylides with activated alkynes
ISSN:0040-4020
1464-5416
DOI:10.1016/S0040-4020(98)00605-X