Potential long-acting contraceptive agents: Esters and ethersof testosterone with α-and/or β-chain branching

The synthesis of ten esters and two ethers of testosterone (17 β-hydroxyandrost-4-en-3-one) is described. All these possess some form of α-and/or β—substitution in the ester/ether sidechain. The work was undertaken in order to evaluate the long-acting antifertility effect of such compounds in males....

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Bibliographic Details
Published inSteroids Vol. 46; no. 6; pp. 947 - 953
Main Authors Herz, J.E., Torres, J.V., Murillo, A., Cruz, S., Shafiee, A., Vosooghi, M., Sotheeswaran, S., Gunatilaka, A.A.L.
Format Journal Article
LanguageEnglish
Published Elsevier Inc 1985
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Summary:The synthesis of ten esters and two ethers of testosterone (17 β-hydroxyandrost-4-en-3-one) is described. All these possess some form of α-and/or β—substitution in the ester/ether sidechain. The work was undertaken in order to evaluate the long-acting antifertility effect of such compounds in males.
ISSN:0039-128X
1878-5867
DOI:10.1016/S0039-128X(85)80002-7