Intraocular Pressure Control Following Phacoemulsification in Eyes With Pre-existing Aurolab Aqueous Drainage Implant

• Published in: Journal of glaucoma Vol. 31; no. 6; p. 456
• Main Authors: Wijesinghe, Hiruni K, Puthuran, George V, Ramulu, Pradeep Y, Ponnat, Arvin K, Reddy, Madhan M, Mani, Iswarya, Krishnadas, Subbaiah R, Gedde, Steven J
• Format: Journal Article
• Language: English
• Published: United States 01.06.2022
• Subjects: Adult; Cataract - complications; Cataract Extraction; Follow-Up Studies; Glaucoma - complications; Glaucoma - surgery; Glaucoma Drainage Implants; Humans; Intraocular Pressure; Phacoemulsification; Retrospective Studies; Treatment Outcome
• ISSN: 1536-481X
• DOI: 10.1097/IJG.0000000000001946

The aim was to investigate intraocular pressure (IOP) control after phacoemulsification in adult glaucomatous eyes with a functioning nonvalved Aurolab Aqueous Drainage Implant (AADI) compared with eyes that did not have cataract extraction post-AADI. In this retrospective study, we reviewed records of 47 patients (47 eyes) who had a clear corneal phacoemulsification after AADI placement with a minimum of 2 years of follow up. The control group included 89 patients (89 eyes) who had a functional AADI at 1 year, minimum of 3 years of follow up post-AADI implantation, and no cataract extraction. The main outcome measure was failure (IOP >21 mm Hg or increased by >20% from prephacoemulsification level requiring at least 1 additional glaucoma medication, IOP ≤5 mm Hg, reoperation for glaucoma, or loss of light perception vision). The median interval between AADI and phacoemulsification was 11.5 months (range: 4 to 68 mo), and the mean follow-up time after phacoemulsification was 35.6±6.4 months. The cumulative probability of failure was 14% (95% confidence interval=6%-31%) in the phaco group and 6% (95% confidence interval=3%-13%) in the control group at 2 years (P=0.11). Mean IOP was reduced from 16.5±4.5 mm Hg preoperatively to 15.4±4.7 mm Hg at 2 years after phacoemulsification (P=0.10). Mean LogMAR visual acuity improved from 1.1±0.6 preoperatively to 0.6±0.7 at 2 years after phacoemulsification (P<0.001). In eyes with a pre-existing AADI, phacoemulsification resulted in visual improvement without a significant rise in IOP or increased risk of AADI failure after 2 years follow up.