Luminescence properties of a nanotheranostics based on a multifunctional Fe3O4/Au/Eu[1-(2-naphthoyl)-3,3,3-trifluoroacetone]3 nanocomposite

• Published in: Optical materials Vol. 109; p. 110229
• Main Authors: Khuyen, Hoang Thi, Huong, Tran Thu, Huong, Nguyen Thanh, Thai Ha, Vu Thi, Van, Nguyen Duc, Nghia, Vu Xuan, Anh, Tran Kim, Minh, Le Quoc
• Format: Journal Article
• Language: English
• Published: Elsevier B.V 01.11.2020
• Subjects: Cellular imaging; Fe3O4; Gold; Luminescent europium complex; Multifunctional nanoparticle; Temperature; Fe3O4; Cellular imaging; Gold; Luminescent europium complex; Temperature; Multifunctional nanoparticle
• ISSN: 0925-3467; 1873-1252
• DOI: 10.1016/j.optmat.2020.110229

The multifunctional Fe3O4/Au/Eu [1-(2-Naphthoyl)-3,3,3-trifluoroacetone]3 nanocomposite (NC) composed of luminescent europium(III) complex with 1-(2-naphthoyl)-3,3,3- trifluoroacetone (NTA) ligands (Eu(NTA)3), superparamagnetic Fe3O4 and plasmonic gold nanoparticles (FAEu(NTA)3) is developed for theranostic application. The FAEu(NTA)3 NC has been functionalized by 3-(mercaptopropyl)trimethoxysilane/3-(triethoxysilyl)-propylamine (MCPMS/TESPA) and conjugated with IgG antibody. This study was focused on luminescent properties and evaluation of the temperature dependent luminescence of FAEu(NTA)3 NC. The in vitro fluorescent imaging test of the prostate cancer PC3 cells incubated with FAEu(NTA)3 NC has been also presented. [Display omitted] •Novel luminescent-magnetic-plasmonic material for nanotheranostics was reported.•Fe3O4/Au/Eu [1-(2-Naphthoyl)-3,3,3-trifluoroacetone]3 nanocomposite was synthesized.•High photostability and enhanced luminescence by Au NPs-induced SPR were achieved.•Photobleaching were avoided.•In-vitro fluorescent imaging of prostate cancer PC3 cells was obviously observed.