Assembling ZnO and Fe3O4 nanostructures on halloysite nanotubes for anti-bacterial assessments

• Published in: Applied surface science Vol. 509; p. 145358
• Main Authors: Jee, Seung-Cheol, Kim, Min, Shinde, Surendra K., Ghodake, Gajanan S., Sung, Jung-Suk, Kadam, Avinash A.
• Format: Journal Article
• Language: English
• Published: Elsevier B.V 15.04.2020
• Subjects: Biofilms; E. coli; Halloysite nanotubes; MRSA; Nano-anti-microbials; S. aureus; S. aureus; Biofilms; Halloysite nanotubes; Nano-anti-microbials; E. coli; MRSA
• ISSN: 0169-4332; 1873-5584
• DOI: 10.1016/j.apsusc.2020.145358

[Display omitted] •HNTs Surface was tuned with ZnO and Fe3O4 nanostructures (M-HNTs-ZnO).•M-HNTs-ZnO found potent-bactericidal to drug-resistant/non-drug-resistant bacteria’s.•M-HNTs-ZnO exhibited significant anti-biofilm properties against S. aureus biofilm.•Its consistent repeated-bactericidal effect marked its importance in water-treatments.•Nano-interface of M-HNTs-ZnO can be vital in clinical/water-purification applications. This study reports anti-bacterial assessments of ‘halloysite nanotubes (HNTs) surface-tuned with Fe3O4 and ZnO nanostructures (M-HNTs-ZnO)’ against the non-drug resistant pathogenic E. coli and S. aureus, drug-resistant methicillin-resistant S. aureus (MRSA) and their respective biofilms. Naturally occurring clay mineral the halloysite nanotubes (HNTs) are emerging materials in nano-bio-medicines. Fabricating HNTs' tunable surface with anti-bacterial nanomaterials can be a significant application in combating the deadly bacterial infections. SEM, TEM, FT-IR, XPS and VSM analysis corroborated a successful synthesis of M-HNTs-ZnO. The acquired results established the significant anti-bacterial potential of M-HNTs-ZnO against the E. coli, S. aureusand MRSA, respectively. The stepwise modifications made on HNTs enhanced anti-bacterial performance. Detailed SEM image analysis established possible anti-bacterial mechanisms. M-HNTs-ZnO found effective against the successfully established biofilms of S. aureus. The M-HNTs-ZnO applied in repeated anti-bacterial performance against E. coli, S. aureusand MRSA, marked its importance for water-treatments. In conclusion, M-HNTs-ZnO showed significant anti-bacterial properties that can be used in the treatment of infectious diseases. Also, its repeated anti-bacterial capabilities might be applied in water disinfection protocols.