The effect of Chlorella vulgaris on obesity related metabolic disorders: a systematic review of randomized controlled trials

(CV) as a unicellular algae is a dietary supplement with beneficial nutritious content, used for decades in some countries. Positive effects for CV supplementation on metabolic parameters has been established in animal and human studies. However there is a gap for this results summary for a definite...

Full description

Saved in:
Bibliographic Details
Published inJournal of complementary & integrative medicine Vol. 19; no. 4; pp. 833 - 842
Main Authors Sanayei, Mahzad, Kalejahi, Parinaz, Mahinkazemi, Mahsa, Fathifar, Zahra, Barzegar, Ali
Format Journal Article
LanguageEnglish
Published Germany De Gruyter 01.12.2022
Walter de Gruyter GmbH
Subjects
Body weight
Clinical research
Clinical trials
Dietary supplements
Glucose
Medical screening
Metabolic disorders
Metabolic syndrome
Obesity
Statistical power
Systematic review
metabolic syndrome
Chlorella vulgaris
obesity
Online AccessGet full text

Cover

More Information
Summary:(CV) as a unicellular algae is a dietary supplement with beneficial nutritious content, used for decades in some countries. Positive effects for CV supplementation on metabolic parameters has been established in animal and human studies. However there is a gap for this results summary for a definite conclusion announce. This systematic review aimed to summarize the effects of CV on body weight, lipid profile, and blood glucose. PRISMA guidelines were charted in this review. Subject search was performed in MEDLINE, ProQuest, PubMed, ISI web of sciences, Google scholar, Cochrane and Scopus databases for randomized clinical trials published in English languages, until December 2020, which assessed the effects of CV on metabolic syndrome related symptoms in clinical trials. Out of 4,821 records screened, after duplicate and irrelevant exclusion by title and abstract, 20 articles remained for full text screening. Finally a total of 12 articles met the study inclusion criteria and were assessed for study method and results. The findings showed controversies in anthropometric, glycemic and lipid profile effects. CV may have beneficial effects on obesity-related metabolic disorders; however, collected studies lacked statistical power to reach a definite conclusion. More well-designed studies are required.
Bibliography:ObjectType-Article-2
SourceType-Scholarly Journals-1
content type line 14
ObjectType-Feature-3
ObjectType-Evidence Based Healthcare-1
ObjectType-Article-1
ObjectType-Feature-2
ObjectType-Review-3
content type line 23
ISSN:2194-6329
1553-3840
1553-3840
DOI:10.1515/jcim-2021-0024