Multidrug resistance Gene-1 polymorphisms (C3435T and G2677T) and the risk of inflammatory bowel disease in Egyptian patients

• Published in: Arab journal of gastroenterology
• Main Authors: Marzaban, Raghda, Mohamed Samy, Rania, Ahmed Kassem, Mona, Atef, Mira
• Format: Journal Article
• Language: English
• Published: Egypt Elsevier B.V 26.02.2024
• Subjects: Crohn’s disease (CD); Inflammatory bowel disease (IBD); Multidrug resistance 1 (MDR1); Single nucleotide polymorphism (SNP); Ulcerative colitis (UC); Inflammatory bowel disease (IBD); Crohn’s disease (CD); Multidrug resistance 1 (MDR1); Ulcerative colitis (UC); Single nucleotide polymorphism (SNP)

The multidrug resistance 1 (MDR1) gene is a gene involved in the pathogenesis of inflammatory bowel disease (IBD).The aim of the study is to investigate the association of MDR-1 gene polymorphisms (C2345T and G2677T) and IBD incidence in Egyptian patients, and its relation with disease severity. Thi...