Low Protein C in Hemodialysis Patients

Protein C activity was studied in 14 hemodialysis patients and compared with 14 healthy, age- and sex-matched controls. Prior to dialysis, protein C activity was depressed in all patients (mean 0.43, range 0.24–0.68 versus mean 1.00, range 0.79–1.14). During dialysis, protein C activity rose but did...

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Bibliographic Details
Published inBlood purification Vol. 2; no. 2; pp. 93 - 97
Main Authors Sørensen, P.J., Knudsen, F., Nielsen, A.H., Dyerberg, J.
Format Journal Article
LanguageEnglish
Published Basel, Switzerland Karger 1984
Subjects
Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy
Biological and medical sciences
Emergency and intensive care: renal failure. Dialysis management
Intensive care medicine
Medical sciences
Original Paper
Hemodialysis
Protein C
Thrombosis
Human
Anti C protein
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Summary:Protein C activity was studied in 14 hemodialysis patients and compared with 14 healthy, age- and sex-matched controls. Prior to dialysis, protein C activity was depressed in all patients (mean 0.43, range 0.24–0.68 versus mean 1.00, range 0.79–1.14). During dialysis, protein C activity rose but did not reach normal levels. The reduced protein C activity may play an important role in the altered hemostatic equilibrium in chronic hemodialysis.
ISSN:0253-5068
1421-9735
DOI:10.1159/000169318