Calcium Ion Detection Using Miniaturized InN-based Ion Sensitive Field Effect Transistors

An Ultrathin (~10 nm) InN ion sensitive field effect transistor (ISFET) with gate regions functionalized with phosphotyrosine (p-Tyr) is proposed to detect calcium ions (Ca2+) in aqueous solution. The ISFET was miniaturized to a chip size of 1.1 mm by 1.5 mm and integrated at the tip of a hypodermic...

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Bibliographic Details
Published inInternational journal of automation and smart technology Vol. 2; no. 1; pp. 49 - 54
Main Authors Kao, Kun-Wei, Su, Yun-Wen, Lu, Yen-Sheng, Gwo, Shangjr, Yeh, J. Andrew
Format Journal Article
LanguageEnglish
Published Chinese Institute of Automation Engineers (CIAE) & Taiwan Smart Living Space Association (SMART LISA) 01.03.2012
Subjects
calcium
indium nitride (InN)
ion-sensitive field-effect transistor (ISFET)
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Summary:An Ultrathin (~10 nm) InN ion sensitive field effect transistor (ISFET) with gate regions functionalized with phosphotyrosine (p-Tyr) is proposed to detect calcium ions (Ca2+) in aqueous solution. The ISFET was miniaturized to a chip size of 1.1 mm by 1.5 mm and integrated at the tip of a hypodermic injection needle (18 G) for real-time and continuous monitoring. The sensor shows a current variation ratio of 1.11% with per decade change of Ca2+ and a detection limit of 10-6 M. The response time of 5 sec. reveals its great potential for accomplishing fast detection in chemical and physiological sensing applications. The sensor would be applied in medical diagnosis and used to monitor continuous and real-time variations of Ca2+ levels in human blood in the near future.
ISSN:2223-9766
2223-9766
DOI:10.5875/ausmt.v2i1.117