Neurotrophic and antioxidant potential of neuropeptides and trace elements

Neurotrophic therapy with brain extract-based drugs has been performed for decades. The basis for their neurotrophic activity is amino acids and neuropeptides. However, incomplete information on the composition of these drugs precludes a detailed description of mechanisms through which their pharmac...

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Published inNevrologii͡a︡, neĭropsikhiatrii͡a︡, psikhosomatika Vol. 7; no. 4; pp. 92 - 100
Main Authors Gromova, O. A., Pronin, A. V., Torshin, I. Yu, Kalacheva, A. G., Grishina, T. R.
Format Journal Article
LanguageEnglish
Published IMA-PRESS LLC 01.01.2016
Subjects
amino acids
cerebral ischemia
cerebrolysin
molecular pharmacology
neuropeptides
neurotrophic factors
superoxide dismutase activity
trace elements
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Summary:Neurotrophic therapy with brain extract-based drugs has been performed for decades. The basis for their neurotrophic activity is amino acids and neuropeptides. However, incomplete information on the composition of these drugs precludes a detailed description of mechanisms through which their pharmacological effects occur. The review considers the results of the most recent molecular pharmacological investigations and the mechanisms of therapeutic action of cerebrolysin.
ISSN:2074-2711
2310-1342
DOI:10.14412/2074-2711-2015-4-92-100