Facile multipoint nanoholes array-based plasmonic platform: Development, characterization, and sensor evaluation

• Published in: Materials letters Vol. 332; p. 133526
• Main Authors: Pereira Cabral Júnior, Bento, Halison de Oliveira, Jean, Henrique Maciel Buzzetti, Paulo, Mitiko Taniguchi, Maiara, Paulo Monteiro, Johny, Henrique Cardozo Amorin, Luís, Urbano, Alexandre, Radovanovic, Eduardo, Marcelo Girotto, Emerson
• Format: Journal Article
• Language: English
• Published: Elsevier B.V 01.02.2023; Elsevier
• Subjects: Biodetection; Biosensor; Chemical Sciences; NSL; Plasmonic holes; Polymer resin; Plasmonic holes; Biodetection; Biosensor; NSL; Polymer resin; biosensor; biodetection; plasmonic holes; Biosensor Plasmonic holes NSL Polymer resin Biodetection; polymer resin
• ISSN: 0167-577X; 1873-4979
• DOI: 10.1016/j.matlet.2022.133526

[Display omitted] •A low-cost SPR biosensor with multi-detection capability was developed.•NSL was used as an alternative method for SPR biosensors.•An alternative polymeric system to multiplex sensing points in thin films.•Demarcated devices with high sensitivity for RI changes.•The biosensor exhibited excellent respond to biomolecules immobilization. This study demonstrates a novel nanoholes array-based plasmonic platform with potential for application in multi-detection analysis. The nanostructured transducer was obtained by nanosphere lithography (NSL), which was restricted to having a sensing multipoint. The microscopic characterization showed sensing point (Sen-P) arrays withca.380 µm and nanoholes with 234.1 ± 27.3 nm diameter. Nanoholes array transmission spectra presented a plasmonic band inca.531 nm when the refractive index (RI) was 1.3397. The plasmonic device showed a RI sensitivity of 271.92 ± 14.92 nm/RIU and could detect the bovine serum albumin (BSA) with good feasibility. These results suggest the potential suitability of our platform to develop multiple monitoring systems.