A chlorhexidine contact lens disinfection tablet: design criteria and antimicrobial efficacy in potable tap water

A contact lens disinfection system (OptimEyes) is described, based on a tablet formulation, which, when added to 10ml of rising mains tap water, provides a disinfection solution containing 0.004% chlorhexidine gluconate in a safe, ophthalmically acceptable vehicle. The design criteria associated wit...

Full description

Saved in:
Bibliographic Details
Published inJournal of the British Contact Lens Association Vol. 14; no. 3; pp. 99 - 108
Main Authors Anthony, Yolande, Davies, David J.G., Meakin, Brian J., Halliday, Janet, Kumar, Ravinder, MacDonald, Ishbel, Ritchie, Margaret
Format Journal Article
LanguageEnglish
Published Elsevier B.V 1991
Subjects
chlorhexidine
Contact lens care
disinfection
OptimEyes
tap water
OptimEyes
chlorhexidine
disinfection
tap water
Contact lens care
Online AccessGet full text

Cover

More Information
Summary:A contact lens disinfection system (OptimEyes) is described, based on a tablet formulation, which, when added to 10ml of rising mains tap water, provides a disinfection solution containing 0.004% chlorhexidine gluconate in a safe, ophthalmically acceptable vehicle. The design criteria associated with the formulation development are discussed and microbiological efficacy data against bacteria ( Staphylococcus aureus, Pseudomonas aeruginosa, Serratia marcescens, Bacillus sp.), moulds and yeasts ( Candida albicans, Aspergillus niger), virus ( Herpes simplex), and Acanthamoeba ( A. castellaniiv A. polyphaga), are provided for the tablet dissolved in representative samples of water. The results demonstrate that rising mains tap water as modified by the OptimEyes formulation provides a microbiologically safe, simple, and highly effective method for lens disinfection, which should promote care regimen compliance.
ISSN:0141-7037
DOI:10.1016/0141-7037(91)80002-4