Subcellular distribution of a gonadotropin-induced form of mouse ovarian arian alkaline phosphate

The subcellular distributions of alkaline phosphatase I (the major activity of prepubertal mouse ovaries) and alkaline phosphatase Ib (a kinetically distinct isoenzyme induced in large amounts by injection of human chorionic gonadotropin and discontinous density gradient centrifugation of ovarin hom...

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Bibliographic Details
Published inBiochimica et biophysica acta. General subjects Vol. 451; no. 1; pp. 118 - 123
Main Author Bramley, Thomas A.
Format Journal Article
LanguageEnglish
Published Elsevier B.V 18.11.1976
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Summary:The subcellular distributions of alkaline phosphatase I (the major activity of prepubertal mouse ovaries) and alkaline phosphatase Ib (a kinetically distinct isoenzyme induced in large amounts by injection of human chorionic gonadotropin and discontinous density gradient centrifugation of ovarin homogenates from control and gonadotropin-treated mice. The distributions of the two alkaline phosphatases were alike and were similar to those of nucleotidase, Mg 2+-dependent ATPase and Co 2+-stimulated naphthylamidase activities, suggesting that they were associated with plasma-membrane vesicles.
ISSN:0304-4165
1872-8006
DOI:10.1016/0304-4165(76)90263-4